It seems that Moon Girl is super-smart and sees the world differently than others. Marvel Comics is really busting that out as something unique, but it reminds me a lot of Amadeus Cho or Big Hero 6's Hiro Hamada. But maybe she'll stand out differently than these other super-smart kids.
Here is one way. It turns out that Lunella is an Inhuman -- at least she's potentially Inhuman. It seems that she has that gene, but it was unclear if she's manifested those powers yet. "She's got an Inhuman gene, unpredictable alien DNA inside that -- once triggered -- could take her life in a wildly different direction. She's determined to control that change."
It looks like Moonboy will make an appearance in this series, as well as one of the Killer-Folk -- the hostile cavemen that originally challenged Devil Dinosaur and Moonboy back in the 1970s. But Devil's new adventures with Moon Girl will take place in the contemporary post-Secret Wars Marvel Comics continuity.